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Effect of intestinal ischemia/reperfusion injury on leptin and orexin-A levels
LIN Ji, YAN Guangtao, HAO Xiuhua, ZHANG Kai, GAO Xiaoning, LIAO Jie
《医学前沿(英文)》 2007年 第1卷 第1期 页码 87-92 doi: 10.1007/s11684-007-0017-3
关键词: significant difference intestinal I/R transcriptase-polymerase metabolic central secretory
null
《医学前沿(英文)》 2016年 第10卷 第3期 页码 278-285 doi: 10.1007/s11684-016-0453-z
Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. We aimed to find novel molecules as potential biomarkers for the early diagnosis of CRC. A serum-free conditioned medium was successfully collected from three pairs of CRC tissue and adjacent normal tissue. iTRAQ-based quantitative proteomic analysis was applied to compare the differences in secretome between primary CRC mucosa and adjacent normal mucosa. A total of 145 kinds of proteins were identified. Of these proteins, 29 were significantly different between CRC and normal tissue. Tropomyosin 2 β (TPM2) exhibited the most significant differences; as such, this protein was selected for further validation. Quantitative real-time PCR indicated that the mRNA expression of TPM2 significantly decreased in the CRC tissue compared with the paired adjacent normal tissue. Immunohistochemical analysis also confirmed that TPM2 was barely detected at protein levels in the CRC tissue. In summary, this study revealed potential molecules for future biomarker applications and provided an efficient approach for the differential analysis of cancer-associated secretome. TPM2 may be valuable for the early diagnosis of CRC.
Hassan YOUSEFI, Alireza TAGHAVI KANI, Iradj MAHMOUDZADEH KANI
《结构与土木工程前沿(英文)》 2019年 第13卷 第2期 页码 429-455 doi: 10.1007/s11709-018-0483-5
关键词: central high resolution schemes RBFs higher order accuracy generalized thermoelasticity multiresolution-based adaptation
Degradation of refractory organics in concentrated leachate by the Fenton process: Central composite
Senem Yazici Guvenc, Gamze Varank
《环境科学与工程前沿(英文)》 2021年 第15卷 第1期 doi: 10.1007/s11783-020-1294-1
关键词: Concentrated leachate Fenton oxidation Central composite design Biodegradability Inert COD
Development of a multi-component drug from turmeric using central composite design
Xiaohang ZHANG,Shengnan HAN,Yan LI,Jianlan JIANG
《化学科学与工程前沿(英文)》 2014年 第8卷 第3期 页码 362-368 doi: 10.1007/s11705-014-1439-5
关键词: multi-component drug development central composite design turmeric curcuminoids
Prevalence of vitamin D deficiency in girls with idiopathic central precocious puberty
null
《医学前沿(英文)》 2018年 第12卷 第2期 页码 174-181 doi: 10.1007/s11684-017-0544-5
The relationship between vitamin D deficiency and idiopathic central precocious puberty (ICPP) has been recently documented. In this study, 280 girls diagnosed with ICPP and 188 normal puberty control girls of similar ages were enrolled and retrospectively studied. The ICPP group had significantly lower serum 25-hydroxyvitamin D (25[OH]D) levels than the control group. Furthermore, a nonlinear relationship was found between serum 25[OH]D and ICPP, and a cut-off point for serum 25[OH]D was found at 31.8 ng/ml for ICPP with and without adjusting the different confounding factors. Girls with serum 25[OH]D≥31.8 ng/ml had a lower odds ratio (unadjusted: OR 0.36, 95% CI 0.15 to 0.83, <0.05; height and weight adjusted: OR 0.44, 95% CI 0.18 to 1.08, = 0.072; BMI adjusted: OR 0.36, 95% CI 0.16 to 0.84, <0.05). The ICPP subjects with 25[OH]D deficiency had a higher body mass index (BMI) than the subjects from the two other subgroups. Correlation analysis showed that vitamin D level is correlated with BMI and some metabolic parameters in the ICPP group. Our study suggested that vitamin D status may be associated with ICPP risk and may have a threshold effect on ICPP.
关键词: idiopathic central precocious puberty threshold effects vitamin D status
Chengwei JING, Qin FU, Xiaojun XU
《医学前沿(英文)》 2009年 第3卷 第1期 页码 45-48 doi: 10.1007/s11684-009-0019-4
关键词: central cord syndrome decompression surgical titanium mesh
Environment and economic feasibility of municipal solid waste central sorting strategy: a case study
Hua ZHANG, Zongguo WEN, Yixi CHEN
《环境科学与工程前沿(英文)》 2016年 第10卷 第4期 doi: 10.1007/s11783-016-0852-z
关键词: Environment and economic feasibility Municipal solid waste (MSW) Waste central sorting Green House
《医学前沿(英文)》 页码 889-906 doi: 10.1007/s11684-023-0994-x
关键词: primary central nervous system lymphoma whole-genome sequencing TMSB4X copy number variation gene mutation
Making central-local relations work: Comparing America and China environmental governance systems
Dan GUTTMAN, SONG Yaqin
《环境科学与工程前沿(英文)》 2007年 第1卷 第4期 页码 418-433 doi: 10.1007/s11783-007-0068-3
曾黄麟,袁慧,刘小芳
《中国工程科学》 2004年 第6卷 第11期 页码 33-37
基于一个约束条件下的非线性规划问题的优化计算思想,把模糊中心聚类中计算输入矢量与中心的距离来实现聚类作为一种优化计算问题,证明了模糊中心聚类方法,取一个适当的属函数,其聚类中心vi为模糊聚类中心价值函数的极小值,推导出了基于模糊中心聚类的模式识别的无导师递推学习方法,提出了模糊中心聚类模式分类神经网络结构,该网络可以实现并行数据处理和模式分类的软划分和硬划分。
Distributed fiber optic monitoring of a CFA pile with a central reinforcement bar bundle
Yi RUI, Nicholas de BATTISTA, Cedric KECHAVARZI, Xiaomin XU, Mei YIN
《结构与土木工程前沿(英文)》 2021年 第15卷 第1期 页码 167-176 doi: 10.1007/s11709-020-0581-z
关键词: continuous flight auger pile static load test central reinforcement bar bundle distributed fiber optic sensor finite element load transfer
Flutter control effect and mechanism of central-slotting for long-span bridges
YANG Yongxin, GE Yaojun, XIANG Haifan
《结构与土木工程前沿(英文)》 2007年 第1卷 第3期 页码 298-304 doi: 10.1007/s11709-007-0039-6
关键词: aerodynamic configuration aerodynamic performance flutter mechanism aerodynamic stability theoretical analysis
Problems of Syrdarya river basin management
Serdar EYEBERENOV, Baijing CAO, Fengting LI
《环境科学与工程前沿(英文)》 2009年 第3卷 第2期 页码 221-225 doi: 10.1007/s11783-009-0015-6
Influence of soft rock-fill material as dam embankment with central bituminous concrete membrane
Peter TSCHERNUTTER
《结构与土木工程前沿(英文)》 2011年 第5卷 第1期 页码 63-70 doi: 10.1007/s11709-010-0016-3
关键词: embankment dam bituminous concrete membrane rock-fill material properties deformation behavior
标题 作者 时间 类型 操作
Effect of intestinal ischemia/reperfusion injury on leptin and orexin-A levels
LIN Ji, YAN Guangtao, HAO Xiuhua, ZHANG Kai, GAO Xiaoning, LIAO Jie
期刊论文
iTRAQ-based quantitative analysis of cancer-derived secretory proteome reveals TPM2 as a potential diagnostic
null
期刊论文
Multiscale RBF-based central high resolution schemes for simulation of generalized thermoelasticity problems
Hassan YOUSEFI, Alireza TAGHAVI KANI, Iradj MAHMOUDZADEH KANI
期刊论文
Degradation of refractory organics in concentrated leachate by the Fenton process: Central composite
Senem Yazici Guvenc, Gamze Varank
期刊论文
Development of a multi-component drug from turmeric using central composite design
Xiaohang ZHANG,Shengnan HAN,Yan LI,Jianlan JIANG
期刊论文
Anterior cervical surgery methods for central cord syndrome without radiographic spinal fracture-dislocation
Chengwei JING, Qin FU, Xiaojun XU
期刊论文
Environment and economic feasibility of municipal solid waste central sorting strategy: a case study
Hua ZHANG, Zongguo WEN, Yixi CHEN
期刊论文
Analysis of the genomic landscape of primary central nervous system lymphoma using whole-genome sequencing
期刊论文
Making central-local relations work: Comparing America and China environmental governance systems
Dan GUTTMAN, SONG Yaqin
期刊论文
Distributed fiber optic monitoring of a CFA pile with a central reinforcement bar bundle
Yi RUI, Nicholas de BATTISTA, Cedric KECHAVARZI, Xiaomin XU, Mei YIN
期刊论文
Flutter control effect and mechanism of central-slotting for long-span bridges
YANG Yongxin, GE Yaojun, XIANG Haifan
期刊论文